Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8069648 | 0.92 | FOLH1 (0.44) | FOLH1HTTSLC1A3SLC1A1CNR1 | |
| SCHEMBL8069819 | 0.91 | MMP2 (0.45) | FOLH1HTTSLC1A3SLC1A1LMNA | |
| SCHEMBL8070175 | 0.90 | FOLH1 (0.42) | FOLH1HTTSLC1A3SLC1A1CNR1 | |
| SCHEMBL8070260 | 0.89 | FOLH1 (0.42) | FOLH1HTTSLC1A3SLC1A1CNR1 | |
| SCHEMBL8068011 | 0.89 | MAPT (0.43) | FOLH1HTTSLC1A3SLC1A1 | |
| SCHEMBL8120934 | 0.89 | HTT (0.48) | FOLH1HTTSLC1A3SLC1A1LMNA | |
| SCHEMBL8068280 | 0.89 | ATM (0.45) | FOLH1HTTSLC1A3SLC1A1CNR1 | |
| SCHEMBL8059164 | 0.88 | FOLH1 (0.42) | FOLH1HTTSLC1A3SLC1A1LMNA | |
| SCHEMBL8069355 | 0.86 | CNR1 (0.47) | CNR1 | |
| SCHEMBL8112045 | 0.86 | FOLH1 (0.45) | FOLH1HTTSLC1A3SLC1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-A1 | NEW NPY ANTAGONISTS | AstraZeneca AB (SE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015498-A1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 1999-04-01 | — | — | WO | disclosed |