Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.48 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.48 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.48 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10869745 | 0.86 | ALDH1A1 (0.68) | POLBALDH1A1CYP3A4MAPK1CNR2 | |
| SCHEMBL10585429 | 0.85 | POLB (0.56) | POLBALDH1A1CYP3A4MAPK1CNR2 | |
| SCHEMBL28164 | 0.84 | GAA (0.61) | POLBALDH1A1GAAGFERABCC9 | |
| SCHEMBL29381324 | 0.84 | GAA (0.61) | POLBALDH1A1GAAGFERABCC9 | |
| SCHEMBL312517 | 0.84 | POLB (0.66) | POLBALDH1A1GAAGFERABCC9 | |
| SCHEMBL29709995 | 0.84 | POLB (0.66) | POLBALDH1A1GAAGFERABCC9 | |
| SCHEMBL6254778 | 0.82 | POLB (0.50) | POLBGAAGFERABCC9ABCC8 | |
| SCHEMBL8046971 | 0.81 | POLB (0.69) | POLBALDH1A1CYP3A4MAPK1GAA | |
| SCHEMBL8529006 | 0.81 | POLB (0.69) | POLBALDH1A1CYP3A4MAPK1GAA | |
| SCHEMBL8652280 | 0.81 | GAA (0.50) | POLBALDH1A1CYP3A4GAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706997-B1 | Sulfonyl compound and thermal-sensitive recording medium using the same | SANKO KAIHATSU KAGAKU KENK (JP) | 1998-03-11 | — | — | EP | claimed |
| CN-1329282-A | Photographic element with ion exchange compound | EASTMAN KODAK CO (US) | 2002-01-02 | — | — | CN | disclosed |
| US-4778932-A | Process for preparing diarylsulfones | NEW JAPAN CHEMICAL CO., LTD. (JP) | 1988-10-18 | — | — | US | disclosed |