SCHEMBL10869745

SCHEMBL10869745

O=S(=O)(c1ccc(Cl)cc1)c1ccccc1S(=O)(=O)c1ccc(Cl)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.68
CYP3A4 P08684 1/20 0.68
MAPK1 P28482 1/20 0.68
CNR2 P34972 1/20 0.60
KMT2A Q03164 2/20 0.56
MEN1 O00255 1/20 0.56
KDM4E B2RXH2 2/20 0.55
PKM P14618 1/20 0.55
HSD11B1 P28845 3/20 0.53
POLB P06746 1/20 0.53
KIF18A Q8NI77 1/20 0.51
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA3 P07451 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2947083 0.89 ALDH1A1 (0.60) ALDH1A1CYP3A4MAPK1CNR2KMT2A
SCHEMBL2034446 0.89 HSD11B1 (0.68) ALDH1A1CYP3A4MAPK1CNR2KMT2A
SCHEMBL7199480 0.86 ALDH1A1 (0.62) ALDH1A1CYP3A4MAPK1CNR2KMT2A
SCHEMBL8526951 0.86 POLB (0.64) ALDH1A1CYP3A4MAPK1CNR2KMT2A
SCHEMBL3446333 0.86 CNR1 (0.58) ALDH1A1CYP3A4MAPK1CNR2KMT2A
SCHEMBL7635059 0.86 ALDH1A1 (0.56) ALDH1A1CYP3A4MAPK1CNR2KMT2A
SCHEMBL9464499 0.86 HTR6 (0.71) ALDH1A1CYP3A4MAPK1CNR2KMT2A
SCHEMBL11452192 0.85 ALDH1A1 (0.60) ALDH1A1CYP3A4MAPK1CNR2KMT2A
SCHEMBL8911211 0.85 ALDH1A1 (0.60) ALDH1A1CYP3A4MAPK1CNR2KMT2A
Sulfuric Acid SCHEMBL28495365 0.84 HSD11B1 (0.63) ALDH1A1CYP3A4MAPK1CNR2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0185237-A1 Thermoplastic moulding compositions BASF Aktiengesellschaft (DE) 1986-06-25 EP disclosed