Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26616888 | 0.80 | MAPT (0.49) | ITGB1ITGA4GAAMAPTMAPK1 | |
| SCHEMBL7561838 | 0.80 | MAPT (0.49) | ITGB1ITGA4GAAMAPTMAPK1 | |
| SCHEMBL18555414 | 0.78 | ALDH1A1 (0.38) | MMP2MMP9PPARGMAPTNPSR1 | |
| SCHEMBL2748097 | 0.78 | ALDH1A1 (0.38) | MMP2MMP9PPARGMAPTNPSR1 | |
| SCHEMBL2235690 | 0.78 | ALDH1A1 (0.44) | PPARGKDM4EGAAMAPTMAPK1 | |
| SCHEMBL27900644 | 0.78 | ALDH1A1 (0.44) | PPARGKDM4EGAAMAPTMAPK1 | |
| SCHEMBL4522437 | 0.76 | KEAP1 (0.50) | KEAP1PPARGKDM4EGAAMAPT | |
| SCHEMBL4527204 | 0.76 | KEAP1 (0.50) | KEAP1PPARGKDM4EGAAMAPT | |
| SCHEMBL8530526 | 0.76 | MAPK1 (0.39) | ITGB1ITGA4PPARGKDM4EGAA | |
| SCHEMBL27744373 | 0.76 | KEAP1 (0.50) | KEAP1PPARGKDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773284-A | REACTING GLYCINE AMIDE WITH BENZALDEHYDE | DSM N.V. (NL) | 1998-06-30 | — | — | US | disclosed |