Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MLYCD | O95822 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6796608 | 0.93 | OPRD1 (0.60) | HPGDALDH1A1MAPTMLYCDOPRD1 | |
| SCHEMBL4576597 | 0.93 | ALDH1A1 (0.63) | HPGDALDH1A1MAPTOPRD1OPRM1 | |
| SCHEMBL6795500 | 0.88 | HPGD (0.52) | HPGDALDH1A1MAPTMLYCDOPRD1 | |
| SCHEMBL5703500 | 0.84 | HPGD (0.73) | HPGDALDH1A1MAPTMLYCDHSP90AA1 | |
| SCHEMBL4472102 | 0.83 | HSP90AA1 (0.58) | HPGDALDH1A1MAPTMLYCDOPRD1 | |
| SCHEMBL8527824 | 0.83 | HPGD (0.58) | HPGDALDH1A1MAPTMLYCDOPRD1 | |
| SCHEMBL1986972 | 0.82 | OPRD1 (0.62) | OPRD1OPRM1 | |
| SCHEMBL18713522 | 0.81 | HPGD (0.56) | HPGDALDH1A1MAPTMLYCDOPRD1 | |
| SCHEMBL6797369 | 0.81 | OPRD1 (0.60) | HPGDALDH1A1MAPTOPRD1OPRM1 | |
| SCHEMBL1934353 | 0.80 | OPRD1 (0.53) | HPGDALDH1A1MAPTMLYCDOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873322-A1 | NOVEL COMPOUNDS WITH ANALGESIC EFFECT | Astra Pharma Inc. (CA) | 1998-10-28 | — | — | EP | disclosed |
| WO-1997023467-A1 | NOVEL COMPOUNDS WITH ANALGESIC EFFECT | ASTRA PHARMA INC. (CA) | 1997-07-03 | — | — | WO | disclosed |