Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PTPRF | P10586 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8902583 | 0.80 | ADRA1A (0.45) | ADRA1AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8531892 | 0.75 | ADRA1A (0.41) | ADRA1AKDM4EALDH1A1MTNR1AMTNR1B | |
| SCHEMBL8528137 | 0.75 | MIF (0.42) | ADRA1ACYP1A2MTNR1AMTNR1BACHE | |
| SCHEMBL8901795 | 0.74 | MIF (0.43) | ADRA1ACYP1A2MTNR1AMTNR1BACHE | |
| SCHEMBL13479460 | 0.73 | ADRA1A (0.55) | ADRA1AKDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL8527998 | 0.71 | ADRA1A (0.47) | ADRA1AKDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL11715823 | 0.70 | ADRA1A (0.41) | ADRA1AKDM4EALDH1A1HPGDMTNR1A | |
| SCHEMBL8901652 | 0.69 | CYP1A2 (0.39) | ADRA1ACYP1A2MTNR1AMTNR1B | |
| SCHEMBL8902157 | 0.68 | ADRA1A (0.40) | ADRA1AKDM4EALDH1A1HPGDMTNR1A | |
| SCHEMBL9802265 | 0.65 | KDM4E (0.39) | ADRA1AKDM4EALDH1A1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5606037-A | Processes antineoplastic heteronaphthoquinones | BIOCHEM PHARMA INC. (CA) | 1997-02-25 | — | — | US | claimed |
| US-5736523-A | ADMINISTERING TO THE MAMMAL SUFFERING FROM CANCER | BIOCHEM PHARMA INC. (CA) | 1998-04-07 | — | — | US | disclosed |
| US-5606037-A | Processes antineoplastic heteronaphthoquinones | BIOCHEM PHARMA INC. (CA) | 1997-02-25 | — | — | US | disclosed |
| US-5593970-A | ANTITUMOR AND ANTCARCINOGENIC AGENTS; TRETMENT OF CANCEROUS BONE MARROW BEFORE REGRAFTING | BIOCHEM PHARMA INC. (CA) | 1997-01-14 | — | — | US | disclosed |
| EP-0659190-A1 | ANTINEOPLASTIC HETERONAPHTHOQUINONES | BIOCHEM PHARMA INC (CA) | 1995-06-28 | — | — | EP | disclosed |
| CN-1094402-A | Antineoplastic heteronaphthoquinones | IAF BIOCHEM INT (CA) | 1994-11-02 | — | — | CN | disclosed |
| WO-1994011382-A1 | ANTINEOPLASTIC HETERONAPHTHOQUINONES | BIOCHEM PHARMA INC. (CA) | 1994-05-26 | — | — | WO | disclosed |