Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 7/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11715823 | 0.82 | ADRA1A (0.41) | ADRA1AKDM4EALDH1A1GLAGAA | |
| SCHEMBL27341140 | 0.77 | ADRA1A (0.38) | ADRA1AADRA2AADRA1DADRA1BKDM4E | |
| SCHEMBL11622890 | 0.76 | ADRA1A (0.38) | ADRA1AADRA2AADRA1DADRA1BKDM4E | |
| SCHEMBL13616713 | 0.73 | ADRA1A (0.50) | ADRA1AMTNR1AMTNR1BCYP19A1 | |
| SCHEMBL8902583 | 0.71 | ADRA1A (0.45) | ADRA1AKDM4EALDH1A1HPGD | |
| SCHEMBL20480100 | 0.70 | CYP1A2 (0.50) | KDM4EALDH1A1GLAHPGDCYP19A1 | |
| SCHEMBL20482276 | 0.70 | CYP1A2 (0.50) | KDM4EALDH1A1GLAHPGDCYP19A1 | |
| SCHEMBL13479460 | 0.70 | ADRA1A (0.55) | ADRA1AKDM4EALDH1A1GLAGAA | |
| SCHEMBL11494605 | 0.69 | ADRA1A (0.53) | ADRA1AMTNR1AMTNR1BCYP19A1 | |
| SCHEMBL8527073 | 0.68 | ADRA1A (0.42) | ADRA1AKDM4EALDH1A1HPGDMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593970-A | ANTITUMOR AND ANTCARCINOGENIC AGENTS; TRETMENT OF CANCEROUS BONE MARROW BEFORE REGRAFTING | BIOCHEM PHARMA INC. (CA) | 1997-01-14 | — | — | US | disclosed |
| EP-0533744-A1 | HETEROCYCLIC ANTHRACYCLIONE AND ANTHRACYCLINE ANALOGS | BIOCHEM PHARMA INC. (CA) | 1993-03-31 | — | — | EP | disclosed |
| WO-1991019725-A2 | HETEROCYCLIC ANTHRACYCLIONE AND ANTHRACYCLINE ANALOGS | BIOCHEM PHARMA INC. (CA) | 1991-12-26 | — | — | WO | disclosed |