Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
| ▸ | EDNRB | P24530 | 1/20 | 0.30 |
| ▸ | EDNRA | P25101 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539263 | 1.00 | HIF1A (0.44) | HIF1AKCNH2TSHRPRMT5CD274 | |
| SCHEMBL8528118 | 0.84 | HIF1A (0.46) | HIF1AKCNH2 | |
| SCHEMBL8527006 | 0.83 | HIF1A (0.46) | HIF1AKCNH2SCN3ACTDSP1 | |
| SCHEMBL8529479 | 0.82 | MAPK1 (0.47) | HIF1AKCNH2 | |
| SCHEMBL8369854 | 0.79 | HIF1A (0.63) | HIF1ATSHR | |
| SCHEMBL8399406 | 0.79 | HIF1A (0.63) | HIF1ATSHR | |
| SCHEMBL8369852 | 0.79 | HIF1A (0.63) | HIF1ATSHR | |
| SCHEMBL8096251 | 0.78 | HIF1A (0.56) | HIF1A | |
| SCHEMBL8096246 | 0.78 | HIF1A (0.56) | HIF1A | |
| SCHEMBL8369944 | 0.78 | HIF1A (0.56) | HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877730-A1 | ARYL ACRYLICS FOR USE AS FUNGICIDE | MONSANTO COMPANY (US) | 1998-11-18 | — | — | EP | disclosed |
| US-5739140-A | AGRICULTURAL FUNGICIDES | MONSANTO COMPANY (US) | 1998-04-14 | — | — | US | disclosed |
| WO-1997016413-A9 | ARYL ACRYLICS FOR USE AS FUNGICIDE | — | 1997-08-14 | — | — | WO | disclosed |
| WO-1997016413-A1 | ARYL ACRYLICS FOR USE AS FUNGICIDE | MONSANTO COMPANY (US) | 1997-05-09 | — | — | WO | disclosed |