Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23677751 | 0.82 | — | — | |
| SCHEMBL2818804 | 0.82 | ALDH1A1 (0.69) | ALDH1A1MEN1POLBAPEX1KMT2A | |
| SCHEMBL17837076 | 0.76 | ALDH1A1 (0.45) | ALDH1A1 | |
| SCHEMBL10025732 | 0.76 | ALDH1A1 (0.45) | ALDH1A1 | |
| SCHEMBL1269985 | 0.75 | ALDH1A1 (0.69) | ALDH1A1MEN1POLBAPEX1KMT2A | |
| SCHEMBL7602370 | 0.73 | ALDH1A1 (0.56) | ALDH1A1MEN1POLBAPEX1KMT2A | |
| SCHEMBL22861878 | 0.73 | — | — | |
| SCHEMBL8526781 | 0.72 | CYP4F2 (0.42) | ALDH1A1MEN1KMT2A | |
| SCHEMBL2945318 | 0.72 | ALDH1A1 (0.64) | ALDH1A1 | |
| SCHEMBL2943010 | 0.72 | ALDH1A1 (0.64) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952375-A | NEURAMINIDASE INHIBITOR FOR INHIBITION OF VIRUSES, IN PARTICULAR INFLUENZA VIRUSES; FDA ORANGE BOOK LISTED PATENT FOR OSELTAMIVIR PHOSPHATE | GILEAD SCIENCES, INC. (US) | 1999-09-14 | — | — | US | disclosed |
| US-5763483-A | NEURAMINIDASE INHIBITOR TREATING INFLUENZA VIRUS INFECTION; OSELTAMIVIR OR THE FREE ACID THEREOF; FDA ORANGE BOOK LISTED PATENT FOR OSELTAMIVIR PHOSPHATE | GILEAD SCIENCES, INC. (US) | 1998-06-09 | — | — | US | disclosed |