Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.75 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | NOS3 | P29474 | 1/20 | 0.51 |
| ▸ | NOS1 | P29475 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7989578 | 0.99 | SIGMAR1 (0.73) | SIGMAR1MEN1KMT2AKCNH2SLC6A3 | |
| SCHEMBL8900932 | 0.94 | SIGMAR1 (0.83) | SIGMAR1MEN1KMT2AKCNH2SLC6A3 | |
| SCHEMBL8525748 | 0.92 | SIGMAR1 (0.90) | SIGMAR1CHRM3 | |
| Hydrochloric Acid SCHEMBL7989870 | 0.91 | SIGMAR1 (0.87) | SIGMAR1TSHRCHRM3 | |
| Hydrochloric Acid SCHEMBL7982333 | 0.84 | SIGMAR1 (0.97) | SIGMAR1TSHR | |
| SCHEMBL25238918 | 0.82 | MEN1 (0.89) | SIGMAR1MEN1KMT2AKCNH2SLC6A3 | |
| SCHEMBL13149771 | 0.81 | MEN1 (0.68) | SIGMAR1MEN1KMT2AKCNH2SLC6A3 | |
| SCHEMBL4140482 | 0.80 | MEN1 (0.66) | SIGMAR1MEN1KMT2AKCNH2SLC6A3 | |
| SCHEMBL3030886 | 0.80 | MEN1 (0.66) | SIGMAR1MEN1KMT2AKCNH2SLC6A3 | |
| SCHEMBL5524549 | 0.79 | MEN1 (0.69) | SIGMAR1MEN1KMT2AKCNH2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |