Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.83 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.56 |
| ▸ | NOS3 | P29474 | 1/20 | 0.55 |
| ▸ | NOS1 | P29475 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8527247 | 0.94 | SIGMAR1 (0.75) | SIGMAR1MEN1KMT2AKCNH2TSHR | |
| Hydrochloric Acid SCHEMBL7989578 | 0.93 | SIGMAR1 (0.73) | SIGMAR1MEN1KMT2AKCNH2TSHR | |
| Hydrochloric Acid SCHEMBL7982333 | 0.90 | SIGMAR1 (0.97) | SIGMAR1TSHRFAAH | |
| SCHEMBL8525748 | 0.86 | SIGMAR1 (0.90) | SIGMAR1FAAHCHRM3 | |
| Hydrochloric Acid SCHEMBL7989870 | 0.85 | SIGMAR1 (0.87) | SIGMAR1TSHRFAAHCHRM3 | |
| SCHEMBL4140482 | 0.84 | MEN1 (0.66) | SIGMAR1MEN1KMT2AKCNH2TSHR | |
| SCHEMBL3030886 | 0.84 | MEN1 (0.66) | SIGMAR1MEN1KMT2AKCNH2TSHR | |
| SCHEMBL544161 | 0.84 | SIGMAR1 (0.68) | SIGMAR1MEN1KMT2ATSHRFAAH | |
| SCHEMBL5524549 | 0.84 | MEN1 (0.69) | SIGMAR1MEN1KMT2AKCNH2TSHR | |
| SCHEMBL2927709 | 0.83 | MEN1 (0.73) | SIGMAR1MEN1KMT2AKCNH2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997014689-A1 | ARYL-PIPERAZINE CYCLIC AMINE DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | PIERRE FABRE MEDICAMENT (FR) | 1997-04-24 | — | — | WO | disclosed |