Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8528893 | 0.89 | OPRM1 (0.49) | OPRK1OPRM1KCNH2SLC6A4IDO1 | |
| SCHEMBL8530045 | 0.83 | IDO1 (0.44) | OPRK1HTR2CSLC6A4HTR2BIDO1 | |
| SCHEMBL16902847 | 0.78 | OPRM1 (0.54) | OPRK1OPRM1KCNH2SLC6A4CHRNB4 | |
| SCHEMBL9986991 | 0.78 | OPRM1 (0.54) | OPRK1OPRM1KCNH2SLC6A4CHRNB4 | |
| SCHEMBL8530467 | 0.76 | IDO1 (0.50) | OPRK1OPRM1KCNH2IDO1CHRNB4 | |
| SCHEMBL2385609 | 0.75 | POLB (0.54) | OPRK1OPRM1KCNH2CHRNB4CHRNA3 | |
| SCHEMBL6063449 | 0.75 | OPRM1 (0.51) | OPRK1OPRM1KCNH2CHRNB4CHRNA3 | |
| Water SCHEMBL27641336 | 0.74 | POLB (0.53) | OPRK1OPRM1KCNH2CHRNB4CHRNA3 | |
| SCHEMBL2387108 | 0.74 | POLB (0.57) | OPRK1OPRM1KCNH2CHRNB4CHRNA3 | |
| SCHEMBL16902846 | 0.72 | OPRM1 (0.52) | OPRK1OPRM1KCNH2SLC6A4CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877730-A1 | ARYL ACRYLICS FOR USE AS FUNGICIDE | MONSANTO COMPANY (US) | 1998-11-18 | — | — | EP | disclosed |
| US-5739140-A | AGRICULTURAL FUNGICIDES | MONSANTO COMPANY (US) | 1998-04-14 | — | — | US | disclosed |
| WO-1997016413-A9 | ARYL ACRYLICS FOR USE AS FUNGICIDE | — | 1997-08-14 | — | — | WO | disclosed |
| WO-1997016413-A1 | ARYL ACRYLICS FOR USE AS FUNGICIDE | MONSANTO COMPANY (US) | 1997-05-09 | — | — | WO | disclosed |