Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.43 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7459424 | 0.91 | HAO1 (0.53) | HAO1MAPK1MAPK14KMT2AGID4 | |
| SCHEMBL14360065 | 0.85 | HAO1 (0.64) | HAO1MAPK1MAPK14KMT2AGID4 | |
| SCHEMBL7083547 | 0.85 | HAO1 (0.64) | HAO1MAPK1MAPK14KMT2AGID4 | |
| SCHEMBL7078660 | 0.85 | GID4 (0.60) | HAO1MAPK1MAPK14KMT2AGID4 | |
| SCHEMBL8530757 | 0.83 | HAO1 (0.55) | HAO1MAPK1MAPK14KMT2AGID4 | |
| SCHEMBL20863587 | 0.81 | HAO1 (0.57) | HAO1MAPK1MAPK14KMT2AGID4 | |
| SCHEMBL7059074 | 0.80 | HAO1 (0.57) | HAO1MAPK1MAPK14KMT2AGID4 | |
| SCHEMBL395087 | 0.79 | GID4 (0.62) | HAO1MAPK1MAPK14KMT2AGID4 | |
| SCHEMBL29842306 | 0.79 | GID4 (0.62) | HAO1MAPK1MAPK14KMT2AGID4 | |
| SCHEMBL11224856 | 0.79 | HAO1 (1.00) | HAO1MAPK1MAPK14KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877730-A1 | ARYL ACRYLICS FOR USE AS FUNGICIDE | MONSANTO COMPANY (US) | 1998-11-18 | — | — | EP | disclosed |
| US-5739140-A | AGRICULTURAL FUNGICIDES | MONSANTO COMPANY (US) | 1998-04-14 | — | — | US | disclosed |
| WO-1997016413-A9 | ARYL ACRYLICS FOR USE AS FUNGICIDE | — | 1997-08-14 | — | — | WO | disclosed |
| WO-1997016413-A1 | ARYL ACRYLICS FOR USE AS FUNGICIDE | MONSANTO COMPANY (US) | 1997-05-09 | — | — | WO | disclosed |
| US-4336397-A | 2,4-Dioxo-4-substituted-1-butanoic acid derivatives useful in treating urinary tract calcium oxalate lithiasis | MERCK & CO., INC. (US) | 1982-06-22 | — | — | US | disclosed |