SCHEMBL8527569

SCHEMBL8527569

CC=CC(=O)NOC(=O)CC

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.31
TP53 P04637 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
MGAM O43451 1/20 0.30
GAA P10253 1/20 0.30
SI P14410 1/20 0.30
MGAM2 Q2M2H8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3683867 0.83 ALDH1A1 (0.31) ALDH1A1TP53L3MBTL1SMN1; SMN2
Methoxymethane SCHEMBL2978772 0.80 SMN1; SMN2 (0.32) SMN1; SMN2
SCHEMBL836331 0.77 ALDH1A1 (0.44) ALDH1A1MGAMGAASIMGAM2
SCHEMBL28129594 0.74
SCHEMBL13268373 0.72
SCHEMBL29486011 0.70
SCHEMBL4897752 0.70 KMT2A (0.39) ALDH1A1MGAMGAASIMGAM2
SCHEMBL12638417 0.70
SCHEMBL27353580 0.70
SCHEMBL5037696 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5807942-A ADDITION POLYMERIZABLE MONOMER UNIT IS ATTACHED TO ENZYME, ANTIBODY, ETC. AND RESULTING COMPOUND IS POLYMERIZED THROUGH DOUBLE BOND WITH ANOTHER MODIFIED ENZYME OR ANTIBODY OR WITH A MONOMER SUCH AS METHACRYLAMIDE, USED IN IMMUNOASSAY NOF CORPORATION (JP) 1998-09-15 US disclosed