Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | XBP1 | P17861 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.56 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407479 | 0.86 | AR (0.63) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL8409105 | 0.84 | MAPT (0.59) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL8903304 | 0.84 | CYP1A2 (0.54) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL8902443 | 0.84 | CYP1A2 (0.54) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL30977691 | 0.83 | EPHX1 (0.74) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL1431941 | 0.83 | EPHX1 (0.74) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL2705806 | 0.83 | MAPT (0.64) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL8410666 | 0.82 | EPHX1 (0.60) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL8530877 | 0.81 | AR (0.58) | SMN1; SMN2CYP1A2CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL29535627 | 0.81 | CYP1A2 (0.51) | MAPTLMNAMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596358-B1 | 0-Phenylenediamines containing fluoroakyl(ene) groups and their use as intermediates in the preparation of benzimidazoles | BAYER AG (DE) | 1998-10-28 | — | — | EP | disclosed |
| US-5484953-A | CHEMICAL INTERMEDIATES FOR BENZIMIDAZOLES FOR INSECTICIDES OR NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-01-16 | — | — | US | disclosed |
| EP-0596358-A1 | 0-Phenylenediamines containing fluoroakyl(ene) groups and their use as intermediates in the preparation of benzimidazoles | BAYER AG (DE) | 1994-05-11 | — | — | EP | disclosed |