SCHEMBL8527708

SCHEMBL8527708

CS(=O)(=O)OCCC(F)=C(F)F

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.48
TSHR P16473 2/20 0.48
LMNA P02545 2/20 0.48
KDM4E B2RXH2 1/20 0.48
ALDH1A1 P00352 1/20 0.48
MMP9 P14780 1/20 0.48
ALOX15 P16050 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4767571 0.80 USP2 (0.46) USP2TSHRLMNAKDM4EALDH1A1
SCHEMBL4186274 0.76 USP2 (0.40) USP2TSHRLMNAKDM4EALDH1A1
SCHEMBL5843472 0.73 KDM4E (0.37) USP2TSHRLMNAKDM4EALDH1A1
SCHEMBL4765474 0.72 KDM4E (0.54) USP2TSHRLMNAKDM4EALDH1A1
SCHEMBL7554603 0.71 ALDH1A1 (0.59) USP2TSHRLMNAKDM4EALDH1A1
SCHEMBL2069595 0.71 LMNA (0.52) USP2TSHRLMNAKDM4EALDH1A1
SCHEMBL27432690 0.71 USP2 (0.46) USP2TSHRLMNAKDM4EALDH1A1
SCHEMBL4767210 0.71 KDM4E (0.58) USP2TSHRLMNAKDM4EALDH1A1
Ethane Dimethane Sulfonate SCHEMBL1336145 0.71 USP2 (0.75) USP2TSHRLMNAKDM4EALDH1A1
SCHEMBL10560477 0.70 USP2 (0.50) USP2TSHRLMNAKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640069-B1 FLUOROALKENYL COMPOUNDS AND THEIR USE AS PEST REPELLENTS MONSANTO CO (US) 1998-11-04 EP claimed
US-5623084-A INSECTICIDES, MITICIDES MONSANTO COMPANY (US) 1997-04-22 US claimed
EP-0640069-A1 FLUOROALKENYL COMPOUNDS AND THEIR USE AS PEST REPELLENTS MONSANTO COMPANY (US) 1995-03-01 EP claimed
WO-1992015555-A2 FLUOROALKENYL COMPOUNDS AND THEIR USE AS PEST REPELLENTS MONSANTO COMPANY (US) 1992-09-17 WO claimed
EP-0640069-B1 FLUOROALKENYL COMPOUNDS AND THEIR USE AS PEST REPELLENTS MONSANTO CO (US) 1998-11-04 EP disclosed
US-5714517-A NEMATOCIDES, INSECTICIDES MONSANTO COMPANY (US) 1998-02-03 US disclosed
US-5693865-A Fluoroalkenyl compounds and their use as pest repellents MONSANTO COMPANY (US) 1997-12-02 US disclosed
EP-0798285-A2 3,4,4-Trifluoro-3-butenoic acid or its methyl ester MONSANTO COMPANY (US) 1997-10-01 EP disclosed
US-5623084-A INSECTICIDES, MITICIDES MONSANTO COMPANY (US) 1997-04-22 US disclosed
US-5561162-A SYSTEMIC PESTICIDES; NEMATOCIDES; INSECTICIDES; MITICIDES; EFFICIENCY; CROPS MONSANTO COMPANY (US) 1996-10-01 US disclosed
US-5457134-A Controlling nematodes, insects, acarids on plants MONSANTO COMPANY (US) 1995-10-10 US disclosed
EP-0640069-A1 FLUOROALKENYL COMPOUNDS AND THEIR USE AS PEST REPELLENTS MONSANTO COMPANY (US) 1995-03-01 EP disclosed
US-5389680-A Insecticides, nematocides, miticides MONSANTO COMPANY (US) 1995-02-14 US disclosed
WO-1992015555-A2 FLUOROALKENYL COMPOUNDS AND THEIR USE AS PEST REPELLENTS MONSANTO COMPANY (US) 1992-09-17 WO disclosed