Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 7/20 | 0.36 |
| ▸ | CNR1 | P21554 | 6/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526982 | 0.84 | GGPS1 (0.38) | S1PR1CREBBPKMT2AACP3 | |
| SCHEMBL8527741 | 0.81 | MEN1 (0.52) | S1PR1PTPN7CREBBPHTR6CNR2 | |
| SCHEMBL8527863 | 0.76 | CREBBP (0.64) | CREBBPCDC25A | |
| SCHEMBL8612789 | 0.75 | CNR2 (0.50) | CNR2CNR1 | |
| SCHEMBL8186050 | 0.74 | ASH1L (0.47) | CREBBPCNR2KMT2A | |
| SCHEMBL4603995 | 0.74 | NPSR1 (0.57) | PTPN7CNR2CNR1NPSR1 | |
| SCHEMBL8531509 | 0.74 | ALDH1A1 (0.40) | CREBBPHTR6CNR2CNR1KMT2A | |
| SCHEMBL25193015 | 0.73 | FABP4 (0.55) | KMT2A | |
| SCHEMBL3307790 | 0.72 | KMT2A (0.60) | KMT2A | |
| SCHEMBL4604311 | 0.72 | CNR2 (0.55) | CNR2CNR1NPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0460679-B1 | Endothelin antagonistic peptide derivatives | BANYU PHARMA CO LTD (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5691315-A | CARDIOVASCULAR DISORDERS; VASODILATOR; BRONCHODILATOR | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5470833-A | Vasodilators, bronchodilators | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-11-28 | — | — | US | disclosed |
| US-5444152-A | Vasolidator or bronchodilator | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-22 | — | — | US | disclosed |
| EP-0460679-A2 | Endothelin antagonistic peptide derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-12-11 | — | — | EP | disclosed |