Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8529730 | 0.99 | ANPEP (0.35) | ANPEPERAP2MAPTFOLH1CA12 | |
| SCHEMBL8533611 | 0.86 | ANPEP (0.40) | ANPEPFOLH1 | |
| SCHEMBL8867297 | 0.78 | FDPS (0.33) | FOLH1FDPS | |
| SCHEMBL8528278 | 0.75 | FOLH1 (0.41) | FOLH1 | |
| SCHEMBL22770 | 0.73 | FOLH1 (0.44) | FOLH1 | |
| SCHEMBL8529495 | 0.73 | FOLH1 (0.40) | FOLH1 | |
| SCHEMBL8532025 | 0.73 | METAP1 (0.41) | FOLH1CA12CA1CA2CA9 | |
| SCHEMBL8527710 | 0.71 | FDPS (0.51) | CA12CA2CA9FDPS | |
| SCHEMBL8531489 | 0.71 | FOLH1 (0.38) | FOLH1 | |
| SCHEMBL8531643 | 0.71 | FOLH1 (0.38) | FOLH1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752999-B1 | 2,4-DIPHOSPHONOGLUTARIC ACID DERIVATIVES, METHODS OF PREPARING SUCH COMPOUNDS AND DRUGS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1998-10-28 | — | — | EP | disclosed |
| US-5698541-A | DISEASES OF CALCIUM METABOLISM; OSTEOPOROSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-12-16 | — | — | US | disclosed |