Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 4/20 | 0.51 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.50 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP14 | P50281 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 10/20 | 0.38 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7853015 | 0.73 | FDPS (0.66) | FDPSGGPS1BTN3A1CA12CA2 | |
| SCHEMBL8529730 | 0.72 | ANPEP (0.35) | CA12CA2CA9 | |
| SCHEMBL8528278 | 0.72 | FOLH1 (0.41) | — | |
| SCHEMBL8528123 | 0.71 | ANPEP (0.37) | FDPSCA12CA2CA9 | |
| SCHEMBL8529495 | 0.70 | FOLH1 (0.40) | — | |
| SCHEMBL22770 | 0.70 | FOLH1 (0.44) | LMNAALDH1A1 | |
| SCHEMBL8533611 | 0.69 | ANPEP (0.40) | MMP8ALDH1A1 | |
| SCHEMBL9114540 | 0.69 | FDPS (0.61) | FDPSGGPS1BTN3A1CA12CA2 | |
| Zoledronic Acid Anhydrous SCHEMBL1586366 | 0.69 | FDPS (1.00) | FDPSGGPS1BTN3A1CA12CA2 | |
| Zoledronic Acid Anhydrous SCHEMBL19054 | 0.69 | FDPS (1.00) | FDPSGGPS1BTN3A1CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752999-B1 | 2,4-DIPHOSPHONOGLUTARIC ACID DERIVATIVES, METHODS OF PREPARING SUCH COMPOUNDS AND DRUGS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1998-10-28 | — | — | EP | disclosed |
| US-5698541-A | DISEASES OF CALCIUM METABOLISM; OSTEOPOROSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-12-16 | — | — | US | disclosed |