Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.43 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8528365 | 1.00 | AHR (0.50) | AHRALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL8526831 | 0.94 | PTGS1 (0.48) | AHRALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL8526872 | 0.94 | AHR (0.50) | AHRALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL8526871 | 0.94 | AHR (0.50) | AHRALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL8526833 | 0.94 | PTGS1 (0.48) | AHRALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL8528873 | 0.93 | ALDH1A1 (0.52) | AHRALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL8528871 | 0.93 | ALDH1A1 (0.52) | AHRALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL8531566 | 0.91 | AHR (0.48) | AHRALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL8531564 | 0.91 | AHR (0.48) | AHRALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL8527280 | 0.91 | ALDH1A1 (0.48) | AHRALDH1A1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733610-B1 | Liquid crystalline compound, liquid crystal composition containing the same and liquid crystal display device | CHISSO CORP (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5635108-A | A HEXYNEDIENE DERIVATIVE | CHISSO CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0733610-A1 | Liquid crystalline compound, liquid crystal composition containing the same and liquid crystal display device | Chisso Corporation (JP) | 1996-09-25 | — | — | EP | disclosed |