Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.52 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.52 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8528873 | 1.00 | ALDH1A1 (0.52) | ALDH1A1LMNASMN1; SMN2MEN1USP2 | |
| SCHEMBL8527625 | 0.97 | LMNA (0.50) | ALDH1A1LMNASMN1; SMN2MEN1USP2 | |
| SCHEMBL8527622 | 0.97 | LMNA (0.50) | ALDH1A1LMNASMN1; SMN2MEN1USP2 | |
| SCHEMBL8531688 | 0.96 | LMNA (0.52) | ALDH1A1LMNASMN1; SMN2MEN1USP2 | |
| SCHEMBL8531685 | 0.96 | LMNA (0.52) | ALDH1A1LMNASMN1; SMN2MEN1USP2 | |
| SCHEMBL8527280 | 0.96 | ALDH1A1 (0.48) | ALDH1A1LMNASMN1; SMN2MEN1USP2 | |
| SCHEMBL8526872 | 0.95 | AHR (0.50) | ALDH1A1LMNASMN1; SMN2MEN1USP2 | |
| SCHEMBL8526871 | 0.95 | AHR (0.50) | ALDH1A1LMNASMN1; SMN2MEN1USP2 | |
| SCHEMBL8531310 | 0.93 | MAPT (0.50) | ALDH1A1LMNASMN1; SMN2MEN1USP2 | |
| SCHEMBL8531313 | 0.93 | MAPT (0.50) | ALDH1A1LMNASMN1; SMN2MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733610-B1 | Liquid crystalline compound, liquid crystal composition containing the same and liquid crystal display device | CHISSO CORP (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5635108-A | A HEXYNEDIENE DERIVATIVE | CHISSO CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0733610-A1 | Liquid crystalline compound, liquid crystal composition containing the same and liquid crystal display device | Chisso Corporation (JP) | 1996-09-25 | — | — | EP | disclosed |