Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.67 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.57 |
| ▸ | TUBB | P07437 | 1/20 | 0.57 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.57 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.57 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.57 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.57 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.57 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.57 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.57 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.57 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.57 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.57 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.57 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.57 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3275502 | 0.90 | NR4A2 (0.71) | NR4A2ALOX5MEN1KMT2ATUBB4A | |
| SCHEMBL3275504 | 0.87 | MEN1 (0.65) | NR4A2ALOX5MEN1KMT2ATUBB4A | |
| SCHEMBL27528293 | 0.83 | TUBB4A (0.60) | ALOX5MEN1KMT2ATUBB4ATUBB | |
| SCHEMBL29219478 | 0.83 | ALDH1A1 (0.50) | NR4A2MEN1KMT2ATUBB4ATUBB | |
| SCHEMBL8532389 | 0.83 | NR4A2 (0.57) | NR4A2ALOX5MEN1KMT2ATUBB4A | |
| SCHEMBL87871 | 0.83 | KDM4E (0.65) | MEN1KMT2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL5438097 | 0.82 | NR4A2 (0.69) | NR4A2ALOX5MEN1KMT2ATUBB4A | |
| SCHEMBL30688567 | 0.82 | NR4A2 (0.60) | NR4A2ALOX5MEN1KMT2ATUBB4A | |
| SCHEMBL29955046 | 0.81 | KDM4E (0.66) | NR4A2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2339411 | 0.81 | KDM4E (0.66) | NR4A2MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786361-A | ANTIATHEROSCLEROSIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-07-28 | — | — | US | disclosed |
| EP-0802198-A2 | Pyridazino-, pyrimido, pyrazino and triazino-indoles | BAYER AG (DE) | 1997-10-22 | — | — | EP | disclosed |