Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | EPOR | P19235 | 4/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8528680 | 0.91 | TDP1 (0.36) | TDP1EPORHDAC1HDAC7CNR1 | |
| SCHEMBL8529309 | 0.86 | CNR1 (0.36) | TDP1CNR1MEN1KMT2AF2 | |
| SCHEMBL7039838 | 0.86 | TDP1 (0.36) | TDP1CNR1MEN1KMT2AITGB3 | |
| SCHEMBL7750689 | 0.86 | MEN1 (0.42) | TDP1CNR1MEN1KMT2AF2 | |
| SCHEMBL7039868 | 0.86 | ITGB3 (0.33) | TDP1EPORHDAC1HDAC7CNR1 | |
| SCHEMBL6901612 | 0.85 | CNR1 (0.43) | TDP1HDAC1HDAC7CNR1KMT2A | |
| SCHEMBL30905434 | 0.85 | CNR1 (0.41) | TDP1EPORCNR1MEN1KMT2A | |
| SCHEMBL1389118 | 0.85 | CNR1 (0.41) | TDP1EPORCNR1MEN1KMT2A | |
| SCHEMBL8121296 | 0.84 | F2 (0.38) | TDP1MEN1KMT2AF2F10 | |
| SCHEMBL4651831 | 0.84 | CNR1 (0.42) | TDP1EPORCNR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |