Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 3/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPY4R | P50391 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7042436 | 0.90 | NPY1R (0.40) | NPY1RF2POLBNPY4R | |
| SCHEMBL8126826 | 0.88 | CNR1 (0.37) | NPY1RF2MAPTNPSR1PRSS1 | |
| SCHEMBL8119276 | 0.87 | MEN1 (0.38) | NPY1RF2MEN1KMT2AMAPT | |
| SCHEMBL8528491 | 0.86 | NPY1R (0.35) | NPY1RF2MEN1KMT2AMAPT | |
| SCHEMBL8124247 | 0.86 | NPY1R (0.42) | NPY1RF2NPY4R | |
| SCHEMBL8111890 | 0.86 | NPY1R (0.35) | NPY1RF2MEN1KMT2AMAPT | |
| SCHEMBL8120508 | 0.86 | F2 (0.38) | NPY1RF2HDAC1MEN1KMT2A | |
| SCHEMBL8112969 | 0.86 | F2 (0.36) | NPY1RF2MEN1KMT2AMAPT | |
| SCHEMBL7037398 | 0.86 | MAPT (0.36) | NPY1RF2HDAC1MEN1KMT2A | |
| SCHEMBL8120178 | 0.86 | NPY1R (0.36) | NPY1RF2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |