Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 5/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2434367 | 0.89 | HTT (0.61) | HTTLMNAMEN1KMT2ATSHR | |
| SCHEMBL26132612 | 0.86 | KMT2A (0.57) | HTTLMNAMEN1KMT2ATSHR | |
| SCHEMBL22187605 | 0.86 | MEN1 (0.57) | HTTLMNAMEN1KMT2ATSHR | |
| SCHEMBL30004340 | 0.81 | KMT2A (0.56) | HTTLMNAMEN1KMT2ATSHR | |
| SCHEMBL3945043 | 0.81 | KMT2A (0.56) | HTTLMNAMEN1KMT2ATSHR | |
| SCHEMBL205059 | 0.81 | MEN1 (1.00) | HTTLMNAMEN1KMT2ATSHR | |
| SCHEMBL8018399 | 0.80 | LMNA (0.67) | HTTLMNAMEN1KMT2ATSHR | |
| SCHEMBL12095462 | 0.79 | MEN1 (0.95) | HTTLMNAMEN1KMT2ATSHR | |
| SCHEMBL12933087 | 0.79 | MEN1 (0.84) | HTTLMNAMEN1KMT2ATSHR | |
| SCHEMBL3945186 | 0.77 | MEN1 (0.51) | HTTLMNAMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675105-B1 | Polyiodinated compounds, process for their preparation and diagnostic composition | GUERBET SA (FR) | 1998-12-23 | — | — | EP | claimed |
| EP-0675105-A1 | Polyiodinated compounds, process for their preparation and diagnostic composition | GUERBET S.A. (FR) | 1995-10-04 | — | — | EP | claimed |
| EP-0675105-B1 | Polyiodinated compounds, process for their preparation and diagnostic composition | GUERBET SA (FR) | 1998-12-23 | — | — | EP | disclosed |
| US-5693311-A | Polyiodinated compounds, process for preparing them and diagnostic compositions | GUERBET S.A. (FR) | 1997-12-02 | — | — | US | disclosed |
| EP-0675105-A1 | Polyiodinated compounds, process for their preparation and diagnostic composition | GUERBET S.A. (FR) | 1995-10-04 | — | — | EP | disclosed |