SCHEMBL8528682

SCHEMBL8528682

C[C@@H](C(=O)ON1C(=O)CCC1=O)N1C(=O)C=CC1=O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.34
SLC1A2 P43004 2/20 0.34
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
BLM P54132 1/20 0.33
WRN Q14191 1/20 0.33
HIF1A Q16665 1/20 0.33
LMNA P02545 2/20 0.32
GSK3A P49840 1/20 0.32
GSK3B P49841 1/20 0.32
HSP90AA1 P07900 1/20 0.31
HTT P42858 1/20 0.31
CACNA1B Q00975 1/20 0.31
APBA1 Q02410 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3186902 1.00 MGLL (0.34) MGLLSLC1A2KMT2AATMALDH1A1
SCHEMBL12545967 0.89 MGLL (0.31) MGLLSLC1A2KMT2AATM
SCHEMBL7259853 0.86 SLC1A2 (0.40) SLC1A2KMT2AATMALDH1A1HPGD
SCHEMBL6032785 0.85 ALDH1A1 (0.36) MGLLALDH1A1HPGDCYP1A2CYP2C19
SCHEMBL30327623 0.85 SLC1A2 (0.41) MGLLSLC1A2KMT2AATMALDH1A1
SCHEMBL24872335 0.84 MGLL (0.35) MGLLKMT2AATMALDH1A1HPGD
SCHEMBL20529475 0.84 MGLL (0.35) MGLLKMT2AATMALDH1A1HPGD
SCHEMBL20147087 0.82 MGLL (0.33) MGLLSLC1A2KMT2AATMALDH1A1
SCHEMBL13851696 0.81 MGLL (0.33) MGLLKMT2AATM
SCHEMBL3735742 0.81 ALDH1A1 (0.36) MGLLKMT2AATMALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3048658-A None JP disclosed
US-5773271-A Compounds from biopolymers and effector substances which are linked via optically active amino acid derivatives, processes for the preparation thereof and the use thereof BEHRING DIAGNOSTICS GMBH (DE) 1998-06-30 US disclosed
US-5744315-A Compounds from biopolymers and effector substances which are linked via optically active amino acid derivatives, processes for the preparation thereof and the use thereof BEHRING DIAGNOSTICS GMBH (DE) 1998-04-28 US disclosed
EP-0407897-B1 Compounds of biopolymers effector substances bonded together by optically active aminoacidic derivatives, process for their preparation and their use BEHRINGWERKE AG (DE) 1996-05-01 EP disclosed
US-5484722-A Biopolymer and effector substance conjugates, process for the preparation thereof and their use BEHRINGWERKE AKTIENGESELLSCHAFT (DE) 1996-01-16 US disclosed
US-5321142-A Compounds from biopolymers and effector substances which are linked via optically active amino acid derivatives, processes for the preparation thereof and the use thereof BEHRINGWERKE AKTIENGESELLSCHAFT (DE) 1994-06-14 US disclosed
JP-H0348658-A COMPOUND FROM BIOPOLYMER AND EFFECTOR SUBSTANCE, AND PREPARATION THEREOF BEHRINGWERKE AG 1991-03-01 JP disclosed
EP-0407897-A1 Compounds of biopolymers effector substances bonded together by optically active aminoacidic derivatives, process for their preparation and their use BEHRINGWERKE Aktiengesellschaft (DE) 1991-01-16 EP disclosed