Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4372634 | 0.85 | MYC (0.51) | TSHRTDP1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL1175576 | 0.82 | TDP1 (0.58) | TSHRTDP1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL4466131 | 0.82 | TSHR (0.49) | TSHRTDP1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL15958968 | 0.81 | TSHR (0.47) | TSHRTDP1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL16084978 | 0.80 | ALDH1A1 (0.49) | TSHRTDP1ALDH1A1SMN1; SMN2ALOX15 | |
| SCHEMBL28849500 | 0.79 | NOTUM (0.36) | TDP1ALDH1A1SLC22A8SMN1; SMN2KMT2A | |
| SCHEMBL15631887 | 0.79 | KMT2A (0.50) | TDP1ALDH1A1POLBL3MBTL1SLC22A8 | |
| SCHEMBL605638 | 0.78 | KDM4E (0.47) | TSHRTDP1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL20769169 | 0.78 | CA1 (0.57) | TSHRTDP1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL29598455 | 0.78 | KDM4E (0.47) | TSHRTDP1ALDH1A1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024017876-A1 | HETEROARYL DERIVATIVES AS DDRs INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-01-25 | — | — | WO | disclosed |
| EP-0545893-B1 | Image-receiving sheet for thermal transfer printing | NEW OJI PAPER CO LTD (JP) | 1998-12-30 | — | — | EP | disclosed |
| EP-0300505-B1 | IMAGE-RECEIVING SHEET FOR THERMAL TRANSFER PRINTING | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1993-10-13 | — | — | EP | disclosed |
| EP-0545893-A1 | Image-receiving sheet for thermal transfer printing | NEW OJI PAPER CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |
| WO-1992007131-A1 | STAIN-RESISTANT SULFONATED AROMATIC POLYMERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-30 | — | — | WO | disclosed |
| US-4837200-A | INTERMEDIATE LAYER OF RESIN INSOLUBLE IN ORGANIC SOLVENTS, IMAGE-RECEIVING LAYER OF SOLUBLE RESIN | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1989-06-06 | — | — | US | disclosed |
| EP-0300505-A2 | Image-receiving sheet for thermal transfer printing | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1989-01-25 | — | — | EP | disclosed |
| US-4720480-A | Sheet for heat transference | DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) | 1988-01-19 | — | — | US | disclosed |