Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 7/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC25A5 | P05141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8902037 | 0.81 | AKT1 (0.44) | AKT1SMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL8900155 | 0.80 | AKT1 (0.47) | AKT1SMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL8900948 | 0.77 | AKT1 (0.42) | AKT1SMN1; SMN2RAB9ALMNAIDO1 | |
| SCHEMBL8531983 | 0.76 | AKT1 (0.46) | AKT1SMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL31237790 | 0.73 | AKT1 (0.49) | AKT1SMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL9755756 | 0.69 | SMN1; SMN2 (0.40) | AKT1SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL2491502 | 0.65 | CDC25B (0.48) | AKT1SMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL30608892 | 0.65 | CDC25B (0.48) | AKT1SMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL2427719 | 0.63 | IDO1 (0.41) | AKT1SMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL29364900 | 0.63 | IDO1 (0.41) | AKT1SMN1; SMN2ALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5606037-A | Processes antineoplastic heteronaphthoquinones | BIOCHEM PHARMA INC. (CA) | 1997-02-25 | — | — | US | claimed |
| US-5736523-A | ADMINISTERING TO THE MAMMAL SUFFERING FROM CANCER | BIOCHEM PHARMA INC. (CA) | 1998-04-07 | — | — | US | disclosed |
| US-5606037-A | Processes antineoplastic heteronaphthoquinones | BIOCHEM PHARMA INC. (CA) | 1997-02-25 | — | — | US | disclosed |