Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | EDNRB | P24530 | 2/20 | 0.33 |
| ▸ | EDNRA | P25101 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755764 | 0.79 | ADORA3 (0.35) | SMN1; SMN2POLBKMT2AMEN1HSD17B10 | |
| SCHEMBL8900155 | 0.77 | AKT1 (0.47) | SMN1; SMN2POLBAKT1KMT2AMEN1 | |
| SCHEMBL9755794 | 0.75 | NQO1 (0.42) | POLBAKT1ALOX5 | |
| SCHEMBL8902037 | 0.75 | AKT1 (0.44) | SMN1; SMN2POLBAKT1KMT2AMEN1 | |
| SCHEMBL8901762 | 0.73 | NQO1 (0.38) | KMT2AMEN1HSD17B10MAPTALDH1A1 | |
| SCHEMBL8901552 | 0.73 | NQO1 (0.38) | KMT2AMEN1HSD17B10MAPTALDH1A1 | |
| SCHEMBL8903047 | 0.73 | NQO1 (0.40) | AKT1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8903328 | 0.73 | NQO1 (0.40) | AKT1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8901784 | 0.73 | TDP1 (0.46) | SMN1; SMN2POLBKMT2AMAPTALDH1A1 | |
| SCHEMBL9521194 | 0.72 | AKT1 (0.35) | AKT1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019725-A2 | HETEROCYCLIC ANTHRACYCLIONE AND ANTHRACYCLINE ANALOGS | BIOCHEM PHARMA INC. (CA) | 1991-12-26 | — | — | WO | disclosed |