SCHEMBL8528868

SCHEMBL8528868

COc1cccc2c1CCCC2c1ccc(C(C)=O)cc1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
TAS1R3 Q7RTX0 3/20 0.47
TAS1R1 Q7RTX1 3/20 0.47
TAS1R2 Q8TE23 3/20 0.47
SIGMAR1 Q99720 1/20 0.44
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42
SLC6A3 Q01959 1/20 0.42
ADRA2A P08913 1/20 0.42
ADRA1A P35348 1/20 0.42
ACHE P22303 1/20 0.41
KDM4C Q9H3R0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8527122 0.85 ADRA2A (0.43) CA1CA2TAS1R3TAS1R1TAS1R2
SCHEMBL28594535 0.83 CA1 (0.49) CA1CA2TAS1R3TAS1R1TAS1R2
SCHEMBL8528202 0.79 CA1 (0.45) CA1CA2TAS1R3TAS1R1TAS1R2
SCHEMBL8528200 0.79 CA1 (0.45) CA1CA2TAS1R3TAS1R1TAS1R2
SCHEMBL8527467 0.76 HAO1 (0.64) TAS1R3TAS1R1
SCHEMBL12662601 0.76 CA1 (0.53) CA1CA2TAS1R3TAS1R1TAS1R2
SCHEMBL9265053 0.74 CA1 (0.51) CA1CA2TAS1R3TAS1R1TAS1R2
SCHEMBL1844443 0.73 CA1 (0.53) CA1CA2TAS1R3TAS1R1TAS1R2
SCHEMBL9325738 0.73 CA1 (0.53) CA1CA2TAS1R3TAS1R1TAS1R2
SCHEMBL7459424 0.73 HAO1 (0.53) SIGMAR1ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0877730-A1 ARYL ACRYLICS FOR USE AS FUNGICIDE MONSANTO COMPANY (US) 1998-11-18 EP disclosed
US-5739140-A AGRICULTURAL FUNGICIDES MONSANTO COMPANY (US) 1998-04-14 US disclosed
WO-1997016413-A9 ARYL ACRYLICS FOR USE AS FUNGICIDE 1997-08-14 WO disclosed
WO-1997016413-A1 ARYL ACRYLICS FOR USE AS FUNGICIDE MONSANTO COMPANY (US) 1997-05-09 WO disclosed