Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.41 |
| ▸ | USP1 | O94782 | 1/20 | 0.41 |
| ▸ | USP19 | O94966 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1618212 | 0.96 | TOP2A (0.58) | TOP2ARAB9ASMN1; SMN2HIF1ANPC1 | |
| SCHEMBL27049196 | 0.94 | TOP2A (0.51) | TOP2ARAB9ASMN1; SMN2HIF1ANPC1 | |
| SCHEMBL2754275 | 0.93 | TOP2A (0.50) | TOP2ARAB9ASMN1; SMN2HIF1ANPC1 | |
| SCHEMBL28689525 | 0.92 | SMN1; SMN2 (0.50) | TOP2ARAB9ASMN1; SMN2HIF1ANPC1 | |
| SCHEMBL28671731 | 0.89 | TOP2A (0.47) | TOP2ARAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL28783146 | 0.89 | ALDH1A1 (0.54) | TOP2ARAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL28676431 | 0.87 | TP53 (0.51) | TOP2ARAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL9604028 | 0.85 | ALOX5 (0.50) | TOP2ARAB9ASMN1; SMN2HIF1ANPC1 | |
| SCHEMBL13426567 | 0.85 | TOP2A (0.47) | TOP2ARAB9ASMN1; SMN2HIF1ANPC1 | |
| SCHEMBL29202868 | 0.85 | SMN1; SMN2 (0.50) | TOP2ARAB9ASMN1; SMN2HIF1ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0701169-B1 | Radiation-sensitive compositions containing fully substituted novolak polymers | OLIN MICROELECTRONIC CHEM INC (US) | 1998-12-30 | — | — | EP | disclosed |
| EP-0490966-B1 | RADIATION-SENSITIVE COMPOSITIONS CONTAINING FULLY SUBSTITUTED NOVOLAK POLYMERS | OLIN MICROELECTRONIC CHEM INC (US) | 1998-11-04 | — | — | EP | disclosed |
| EP-0701169-A1 | Radiation-sensitive compositions containing fully substituted novolak polymers | OCG MICROELECTRONIC MATERIALS, INC. (US) | 1996-03-13 | — | — | EP | disclosed |
| EP-0490966-A4 | RADIATION-SENSITIVE COMPOSITIONS CONTAINING FULLY SUBSTITUTED NOVOLAK POLYMERS | — | 1992-10-21 | — | — | EP | disclosed |
| EP-0490966-A1 | RADIATION-SENSITIVE COMPOSITIONS CONTAINING FULLY SUBSTITUTED NOVOLAK POLYMERS | OCG MICROELECTRONICS MATERIALS, INC. (US) | 1992-06-24 | — | — | EP | disclosed |
| WO-1991003769-A1 | RADIATION-SENSITIVE COMPOSITIONS CONTAINING FULLY SUBSTITUTED NOVOLAK POLYMERS | OLIN HUNT SPECIALTY PRODUCTS INC. (US) | 1991-03-21 | — | — | WO | disclosed |