SCHEMBL8528969

SCHEMBL8528969

COc1cc(S(=O)(=O)O)c(N=Nc2c(S(=O)(=O)O)cc3cc(N)ccc3c2O)cc1S(=O)(=O)O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PHLPP2 Q6ZVD8 1/20 0.68
▸ ENPP2 Q13822 8/20 0.51
▸ CD40 P25942 1/20 0.44
▸ CD40LG P29965 1/20 0.44
▸ MEN1 O00255 2/20 0.44
▸ KMT2A Q03164 2/20 0.44
▸ ALDH1A1 P00352 2/20 0.44
▸ KDM4E B2RXH2 1/20 0.44
▸ TP53 P04637 1/20 0.44
▸ CYP3A4 P08684 1/20 0.44
▸ MAPT P10636 1/20 0.44
▸ THRB P10828 1/20 0.44
▸ HPGD P15428 1/20 0.44
▸ ALOX15 P16050 1/20 0.44
▸ APEX1 P27695 1/20 0.44
▸ MAPK1 P28482 1/20 0.44
▸ BRCA1 P38398 1/20 0.44
▸ RECQL P46063 1/20 0.44
▸ BLM P54132 1/20 0.44
▸ SLC10A1 Q14973 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18218279 0.88 PHLPP2 (0.54) PHLPP2ENPP2CD40CD40LGMEN1
SCHEMBL10351172 0.87 PHLPP2 (0.53) PHLPP2ENPP2CD40CD40LGMEN1
SCHEMBL8528964 0.87 PHLPP2 (0.53) PHLPP2ENPP2CD40CD40LGMEN1
SCHEMBL14493323 0.86 PHLPP2 (0.58) PHLPP2ENPP2CD40CD40LGMEN1
SCHEMBL10866274 0.85 PHLPP2 (0.63) PHLPP2ENPP2CD40CD40LGMEN1
SCHEMBL8059751 0.85 PHLPP2 (0.62) PHLPP2ENPP2CD40CD40LGMEN1
SCHEMBL7770984 0.85 PHLPP2 (0.62) PHLPP2ENPP2CD40CD40LGMEN1
SCHEMBL8904069 0.84 PHLPP2 (0.56) PHLPP2ENPP2CD40CD40LGMEN1
SCHEMBL8958917 0.84 PHLPP2 (0.56) PHLPP2ENPP2CD40CD40LGMEN1
SCHEMBL10600174 0.84 PHLPP2 (0.60) PHLPP2ENPP2CD40CD40LGMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5770707-A COLORFAST REACTIVE DYES FOR COTTON SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-06-23 — — US claimed
EP-0728817-A2 Monoazo compounds and dyeing or printing methods using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-08-28 — — EP claimed
US-4772323-A IMPROVED STORAGE AND EJECTION STABILITY CANON KABUSHIKI KAISHA (JP) 1988-09-20 — — US claimed
EP-1795562-A2 Fiber reactive dyestuffs Everlight USA, Inc. (US) 2007-06-13 — — EP disclosed
US-5770707-A COLORFAST REACTIVE DYES FOR COTTON SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-06-23 — — US disclosed
EP-0728817-A2 Monoazo compounds and dyeing or printing methods using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-08-28 — — EP disclosed
EP-0219232-B1 WATER-SOLUBLE DYE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-08-29 — — EP disclosed
US-4772323-A IMPROVED STORAGE AND EJECTION STABILITY CANON KABUSHIKI KAISHA (JP) 1988-09-20 — — US disclosed
US-4758658-A Water-soluble formazan dye IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-07-19 — — US disclosed
EP-0219232-A2 Water-soluble dye IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-04-22 — — EP disclosed
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