SCHEMBL8529029

SCHEMBL8529029

C=CC(=O)N(CCCC)C(=O)CO

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 3/20 0.41
ZDHHC2 Q9UIJ5 2/20 0.41
TSHR P16473 3/20 0.36
HPGD P15428 1/20 0.36
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA9 Q16790 2/20 0.34
FAAH O00519 1/20 0.33
ALDH1A1 P00352 2/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP3 P08254 1/20 0.32
MMP8 P22894 1/20 0.32
THRA P10827 2/20 0.31
THRB P10828 2/20 0.31
CNR1 P21554 2/20 0.30
CNR2 P34972 1/20 0.30
TRPV1 Q8NER1 1/20 0.30
KDM5A P29375 2/20 0.30
KDM4C Q9H3R0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14142921 0.87 ZDHHC20 (0.42) ZDHHC20ZDHHC2TSHRHPGDCA12
SCHEMBL10664833 0.86 ZDHHC20 (0.47) ZDHHC20ZDHHC2TSHRHPGDCA12
SCHEMBL22923570 0.81 ZDHHC20 (0.44) ZDHHC20ZDHHC2TSHRHPGDCA12
SCHEMBL8743186 0.81 ZDHHC20 (0.44) ZDHHC20ZDHHC2TSHRHPGDCA12
SCHEMBL8743344 0.79 ZDHHC20 (0.42) ZDHHC20ZDHHC2TSHRHPGDCA12
SCHEMBL6834024 0.79 TSHR (0.42) ZDHHC20ZDHHC2TSHRHPGDCA12
SCHEMBL25108824 0.79 ZDHHC20 (0.57) ZDHHC20ZDHHC2TSHRHPGDFAAH
SCHEMBL10657941 0.79 ZDHHC20 (0.57) ZDHHC20ZDHHC2TSHRHPGDFAAH
SCHEMBL372729 0.79 ZDHHC20 (0.57) ZDHHC20ZDHHC2TSHRHPGDFAAH
SCHEMBL7647635 0.79 ZDHHC20 (0.57) ZDHHC20ZDHHC2TSHRHPGDFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5763546-A FREE RADICAL SOLUTION POLYMERIZATION; ADDITION POLYMERIZATION, CROSSLINKING BASF LACKE+FARBEN, AG (DE) 1998-06-09 US disclosed