Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 12/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | NPY4R | P50391 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526244 | 0.95 | TDP1 (0.38) | TDP1NPY1RTACR1MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL7040972 | 0.89 | NPY1R (0.38) | NPY1RNPY4RNPFFR1 | |
| Trifluoroacetic Acid SCHEMBL7037784 | 0.86 | TDP1 (0.41) | TDP1NPY1RTACR1NPY4RMEN1 | |
| SCHEMBL8612537 | 0.85 | NPY1R (0.42) | NPY1RMEN1KMT2ANPFFR1CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL8525691 | 0.84 | NPY1R (0.39) | TDP1NPY1RNPY4RNPFFR1 | |
| Trifluoroacetic Acid SCHEMBL8528581 | 0.84 | NPY1R (0.39) | NPY1RNPY4RNPFFR1 | |
| Trifluoroacetic Acid SCHEMBL4699162 | 0.84 | PPID (0.45) | NPY1RNPFFR1 | |
| Trifluoroacetic Acid SCHEMBL9199026 | 0.83 | NPY1R (0.38) | TDP1NPY1RTACR1NPY4R | |
| Trifluoroacetic Acid SCHEMBL8527205 | 0.83 | TACR1 (0.39) | TDP1NPY1RTACR1NPY4RMEN1 | |
| Trifluoroacetic Acid SCHEMBL8528210 | 0.82 | NPY1R (0.37) | NPY1RNPY4RNPFFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |