Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8530065 | 0.81 | FOLH1 (0.39) | FOLH1 | |
| SCHEMBL8530070 | 0.81 | FOLH1 (0.39) | FOLH1 | |
| SCHEMBL1369232 | 0.80 | ALDH1A1 (0.38) | ALDH1A1TSHR | |
| SCHEMBL8528278 | 0.80 | FOLH1 (0.41) | FOLH1 | |
| SCHEMBL22770 | 0.78 | FOLH1 (0.44) | FOLH1ALDH1A1TSHR | |
| SCHEMBL8529495 | 0.78 | FOLH1 (0.40) | FOLH1 | |
| SCHEMBL8529284 | 0.77 | FOLH1 (0.37) | FOLH1 | |
| SCHEMBL8531489 | 0.75 | FOLH1 (0.38) | FOLH1 | |
| SCHEMBL8531643 | 0.75 | FOLH1 (0.38) | FOLH1 | |
| SCHEMBL8532196 | 0.74 | FOLH1 (0.37) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752999-B1 | 2,4-DIPHOSPHONOGLUTARIC ACID DERIVATIVES, METHODS OF PREPARING SUCH COMPOUNDS AND DRUGS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1998-10-28 | — | — | EP | disclosed |
| US-5698541-A | DISEASES OF CALCIUM METABOLISM; OSTEOPOROSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-12-16 | — | — | US | disclosed |
| WO-1995011249-A1 | 2,4-DIPHOSPHONOGLUTARIC ACID DERIVATIVES, METHODS OF PREPARING THEM AND DRUGS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-27 | — | — | WO | disclosed |