Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5363414 | 0.88 | ALDH1A1 (0.34) | ALDH1A1TSHR | |
| SCHEMBL19244726 | 0.83 | ALDH1A1 (0.32) | ALDH1A1TSHRHTT | |
| SCHEMBL8529090 | 0.80 | FOLH1 (0.37) | ALDH1A1TSHR | |
| SCHEMBL7252347 | 0.77 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL2364327 | 0.75 | PPARD (0.32) | ALDH1A1TSHR | |
| SCHEMBL11498320 | 0.74 | ALDH1A1 (0.36) | ALDH1A1TSHRHTTKMT2A | |
| SCHEMBL5824325 | 0.73 | — | — | |
| Acrylic Acid SCHEMBL28624579 | 0.72 | LMNA (0.40) | ALDH1A1TSHR | |
| SCHEMBL19212018 | 0.70 | LPAR2 (0.31) | ALDH1A1TSHR | |
| SCHEMBL2392569 | 0.70 | CYP4F2 (0.33) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2508521-B1 | Dimaleat of an amino crotonyl compound and method of production thereof | BOEHRINGER INGELHEIM INT (DE) | 2015-12-30 | — | — | EP | claimed |
| EP-1678165-B1 | METHOD FOR THE PRODUCTION OF AMINO CROTONYL COMPOUNDS | BOEHRINGER INGELHEIM INT (DE) | 2013-09-25 | — | — | EP | claimed |
| US-8426586-B2 | Using a acyl bromine compound; activation with phosphonacetic acid | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-04-23 | — | — | US | claimed |
| US-20070027170-A1 | Process for preparing amino crotonyl compounds | SOYKA RAINER | 2007-02-01 | — | — | US | claimed |
| US-20050085495-A1 | Process for preparing amino crotonyl compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-04-21 | — | — | US | claimed |
| US-20140248317-A1 | TREHALOSE COMPOUND, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL PRODUCT CONTAINING THE COMPOUND | GLYTECH, INC. (JP) | 2014-09-04 | — | — | US | disclosed |
| US-8426586-B2 | Using a acyl bromine compound; activation with phosphonacetic acid | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-04-23 | — | — | US | disclosed |
| EP-2567963-A1 | Trehalose compound, method for producing same, and pharmaceutical product containing the compound | Otsuka Chemical Co., Ltd. (JP) | 2013-03-13 | — | — | EP | disclosed |
| EP-1981863-B1 | PROCESS FOR PREPARING AMINOCROTONYLAMINO-SUBSTITUTED QUINAZOLINE DERIVATIVES | BOEHRINGER INGELHEIM INT (DE) | 2012-10-10 | — | — | EP | disclosed |
| US-8188274-B2 | Process for preparing aminocrotonylamino-substituted quinazoline derivatives | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-05-29 | — | — | US | disclosed |
| US-8067593-B2 | Process for preparing aminocrotonylamino-substituted quinazoline derivatives | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-11-29 | — | — | US | disclosed |
| US-20110207929-A1 | Process for preparing aminocrotonylamino-substituted quinazoline derivatives | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-08-25 | — | — | US | disclosed |
| US-20110207932-A1 | Process for preparing aminocrotonylamino-substituted quinazoline derivatives | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-08-25 | — | — | US | disclosed |
| US-7960546-B2 | Process for preparing aminocrotonylamino-substituted quinazoline derivatives | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-06-14 | — | — | US | disclosed |
| US-20090306378-A1 | PROCESS FOR PREPARING AMINOCROTONYLAMINO-SUBSTITUTED QUINAZOLINE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-12-10 | — | — | US | disclosed |
| US-20070027170-A1 | Process for preparing amino crotonyl compounds | SOYKA RAINER | 2007-02-01 | — | — | US | disclosed |
| US-20050085495-A1 | Process for preparing amino crotonyl compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140248317-A1 | TREHALOSE COMPOUND, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL PRODUCT CONTAINING THE COMPOUND | TREH, MAN2B1, NFATC1 | ALDH1A1 1285/4885TSHR 2522/4885HTT 2692/4885 |
| US-20070027170-A1 | Process for preparing amino crotonyl compounds | CROCC, CMA1, IL4I1 | ALDH1A1 681/4885TSHR 4643/4885HTT 2716/4885 |
| US-20110207932-A1 | Process for preparing aminocrotonylamino-substituted quinazoline derivatives | EGFR, CNKSR1, ERBB2 | ALDH1A1 3573/4885TSHR 49/4885HTT 3949/4885 |
| US-20090306378-A1 | PROCESS FOR PREPARING AMINOCROTONYLAMINO-SUBSTITUTED QUINAZOLINE DERIVATIVES | EGFR, CNKSR1, ERBB2 | ALDH1A1 3870/4885TSHR 80/4885HTT 4346/4885 |
| US-20110207929-A1 | Process for preparing aminocrotonylamino-substituted quinazoline derivatives | EGFR, CNKSR1, ERBB2 | ALDH1A1 3573/4885TSHR 49/4885HTT 3949/4885 |
| US-20050085495-A1 | Process for preparing amino crotonyl compounds | INMT, IL4I1, HNMT | ALDH1A1 1062/4885TSHR 4742/4885HTT 3714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.