Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 3/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8529151 | 1.00 | ECE1 (0.33) | ECE1EPHX1CA1CA2CA7 | |
| SCHEMBL8529461 | 1.00 | ECE1 (0.33) | ECE1EPHX1CA1CA2CA7 | |
| SCHEMBL16682790 | 0.83 | ECE1 (0.37) | ECE1ALDH1A1 | |
| SCHEMBL18273753 | 0.83 | ECE1 (0.37) | ECE1ALDH1A1 | |
| SCHEMBL20363304 | 0.83 | ECE1 (0.33) | ECE1ALDH1A1 | |
| SCHEMBL18273752 | 0.83 | SLC22A6 (0.36) | — | |
| SCHEMBL10034713 | 0.81 | ECE1 (0.34) | ECE1CA1CA2CA7CA14 | |
| SCHEMBL1705139 | 0.81 | ECE1 (0.34) | ECE1CA1CA2CA7CA14 | |
| SCHEMBL6698272 | 0.79 | ALDH1A1 (0.30) | ECE1ALDH1A1 | |
| SCHEMBL6698270 | 0.78 | MMP1 (0.32) | ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110799215-A | Methods of treating Dravet syndrome | 卡维昂公司 | 2020-02-14 | — | — | CN | claimed |
| CN-110770221-A | Methods for improving memory and cognition and for treating memory and cognitive disorders | 卡维昂公司 | 2020-02-07 | — | — | CN | claimed |
| EP-0827507-A1 | PROTEASE INHIBITING SUCCINIC ACID DERIVATIVES | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 1998-03-11 | — | — | EP | claimed |
| WO-1996031527-A1 | PROTEASE INHIBITING SUCCINIC ACID DERIVATIVES | BOEHRINGER INGELHEIM (CANADA) LTD./BOEHRINGER INGELHEIM (CANADA) LTÉE. (CA) | 1996-10-10 | — | — | WO | claimed |
| EP-0827507-A1 | PROTEASE INHIBITING SUCCINIC ACID DERIVATIVES | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 1998-03-11 | — | — | EP | disclosed |
| WO-1996031527-A1 | PROTEASE INHIBITING SUCCINIC ACID DERIVATIVES | BOEHRINGER INGELHEIM (CANADA) LTD./BOEHRINGER INGELHEIM (CANADA) LTÉE. (CA) | 1996-10-10 | — | — | WO | disclosed |