Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 17/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.50 |
| ▸ | NPY4R | P50391 | 2/20 | 0.50 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.49 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.49 |
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526442 | 0.89 | NPY1R (0.57) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL1388524 | 0.88 | NPY1R (0.49) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL5317095 | 0.88 | NPY1R (0.49) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL7751683 | 0.87 | NPY1R (0.62) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL8587072 | 0.87 | NPY1R (0.52) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL7745901 | 0.86 | CNR1 (0.56) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL6899864 | 0.84 | NPY1R (0.71) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL7059807 | 0.84 | NPY1R (0.71) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL650331 | 0.84 | NPY1R (0.72) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL4651828 | 0.84 | NPY1R (0.61) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |