Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
| ▸ | TACR1 | P25103 | 2/20 | 0.47 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.46 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 4/20 | 0.45 |
| ▸ | CTSK | P43235 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8529450 | 1.00 | SCN9A (0.49) | SCN9ATACR1GSTP1GSTM2MEN1 | |
| SCHEMBL10904975 | 0.91 | CTSK (0.47) | SCN9AGSTP1GSTM2MEN1KMT2A | |
| SCHEMBL15947606 | 0.91 | GSTP1 (0.52) | TACR1GSTP1GSTM2MEN1KMT2A | |
| SCHEMBL30829401 | 0.87 | ACE (0.53) | SCN9ACTSSCTSK | |
| SCHEMBL391142 | 0.87 | ACE (0.53) | SCN9ACTSSCTSK | |
| SCHEMBL648928 | 0.87 | ACE (0.53) | SCN9ACTSSCTSK | |
| SCHEMBL649126 | 0.87 | ACE (0.53) | SCN9ACTSSCTSK | |
| SCHEMBL30829406 | 0.87 | ACE (0.53) | SCN9ACTSSCTSK | |
| SCHEMBL27814764 | 0.85 | KMT2A (0.41) | SCN9AMEN1KMT2ACYP2C19ALDH1A1 | |
| SCHEMBL12869935 | 0.84 | CTSS (0.52) | TACR1CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705257-B1 | AMINOACID DERIVATIVES AS NO SYNTHASE INHIBITORS | WELLCOME FOUND (GB) | 1998-03-11 | — | — | EP | disclosed |