Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8529459 | 1.00 | ROCK2 (0.32) | ROCK2ROCK1ABCB1 | |
| SCHEMBL8528544 | 0.78 | MEN1 (0.30) | — | |
| SCHEMBL8528540 | 0.78 | MEN1 (0.30) | — | |
| SCHEMBL11091145 | 0.77 | ROCK2 (0.37) | ROCK2ROCK1 | |
| SCHEMBL8378509 | 0.74 | ROCK2 (0.39) | ROCK2ROCK1 | |
| SCHEMBL9344725 | 0.74 | MAPT (0.46) | — | |
| SCHEMBL9623442 | 0.74 | MAPT (0.46) | — | |
| SCHEMBL9344729 | 0.74 | MAPT (0.46) | — | |
| SCHEMBL11311725 | 0.72 | MAPT (0.39) | — | |
| SCHEMBL11311717 | 0.72 | POLB (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620228-B1 | Novel reactive thiophosphate derivatives of thia(dia)zole acetic acid and process for preparing the same | LUCKY LTD (KR) | 1998-03-11 | — | — | EP | claimed |
| EP-0620228-A1 | Novel reactive thiophosphate derivatives of thia(dia)zole acetic acid and process for preparing the same | LUCKY LTD. (KR) | 1994-10-19 | — | — | EP | claimed |
| EP-0620228-B1 | Novel reactive thiophosphate derivatives of thia(dia)zole acetic acid and process for preparing the same | LUCKY LTD (KR) | 1998-03-11 | — | — | EP | disclosed |
| US-5502200-A | Reactive thiophosphate derivatives of thia(dia)zole acetic acid and process for preparing the same | LUCKY, LTD. (KR) | 1996-03-26 | — | — | US | disclosed |
| EP-0620228-A1 | Novel reactive thiophosphate derivatives of thia(dia)zole acetic acid and process for preparing the same | LUCKY LTD. (KR) | 1994-10-19 | — | — | EP | disclosed |