Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | PTGIR | P43119 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8530539 | 0.93 | PDE4A (0.39) | MTNR1AMTNR1BPDE4APDE4BPDE4C | |
| SCHEMBL8530423 | 0.85 | MTNR1A (0.38) | MTNR1AMTNR1BPDE4APDE4BPDE4C | |
| SCHEMBL8530641 | 0.82 | ACSL1 (0.37) | MTNR1AMTNR1BPDE4APDE4BPDE4C | |
| SCHEMBL8530624 | 0.74 | MAPT (0.39) | MTNR1APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8530419 | 0.69 | FFAR1 (0.40) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL7457347 | 0.69 | TSHR (0.50) | MAPTALOX15HIF1A | |
| SCHEMBL27446293 | 0.69 | TSHR (0.50) | MAPTALOX15HIF1A | |
| SCHEMBL8530035 | 0.69 | HAO1 (0.37) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL8527421 | 0.69 | KDM4E (0.33) | MTNR1AMTNR1BEPHX2SLC6A4HIF1A | |
| SCHEMBL8530444 | 0.67 | HIF1A (0.35) | CYP1A2MAPTCYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739140-A | AGRICULTURAL FUNGICIDES | MONSANTO COMPANY (US) | 1998-04-14 | — | — | US | disclosed |