SCHEMBL8529496

SCHEMBL8529496

CCOC(=O)C(Cl)=Cc1cc(NC(=O)CC(C)CC(=O)O)ccc1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.44
KDM4E B2RXH2 2/20 0.44
HSD17B10 Q99714 1/20 0.44
POLB P06746 1/20 0.44
KMT2A Q03164 3/20 0.41
CYP3A4 P08684 2/20 0.41
MEN1 O00255 2/20 0.41
MAPT P10636 2/20 0.41
HTT P42858 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
RECQL P46063 1/20 0.41
TSHR P16473 1/20 0.39
HPGD P15428 1/20 0.38
LMNA P02545 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
RORC P51449 3/20 0.37
SLC1A3 P43003 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7933664 0.81 DGAT1 (0.48) ALDH1A1KDM4EHSD17B10POLBKMT2A
SCHEMBL7933665 0.81 DGAT1 (0.48) ALDH1A1KDM4EHSD17B10POLBKMT2A
SCHEMBL8927073 0.81 TSHR (0.39) ALDH1A1KDM4EPOLBKMT2ACYP3A4
SCHEMBL7931184 0.80 KMT2A (0.42) ALDH1A1KDM4EHSD17B10KMT2ACYP3A4
SCHEMBL7931186 0.80 KMT2A (0.42) ALDH1A1KDM4EHSD17B10KMT2ACYP3A4
SCHEMBL7020494 0.78 MAPT (0.41) ALDH1A1KDM4EPOLBKMT2AMEN1
SCHEMBL7017572 0.78 MAPT (0.41) ALDH1A1KDM4EPOLBKMT2AMEN1
SCHEMBL7109287 0.76 GAA (0.41) ALDH1A1KDM4EKMT2AMEN1MAPT
SCHEMBL8304677 0.76 NPSR1 (0.50) KMT2ALMNA
SCHEMBL7762961 0.73 NPSR1 (0.39) ALDH1A1KDM4EKMT2AMAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0666848-B1 SUBSTITUTED N-PHENYLGLUTARIMIDES AND N-PHENYLGLUTARIC ACID AMIDES, THEIR PREPARATION AND USE IN AGRICULTURE BASF AG (DE) 1998-12-30 EP disclosed
WO-1994010147-A1 SUBSTITUTED N-PHENYLGLUTARIMIDES AND N-PHENYLGLUTARIC ACID AMIDES, THEIR PREPARATION AND USE IN AGRICULTURE BASF AKTIENGESELLSCHAFT (DE) 1994-05-11 WO disclosed