Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8529496 | 0.81 | ALDH1A1 (0.44) | TSHRKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL7933664 | 0.78 | DGAT1 (0.48) | KDM4EALDH1A1HPGDMAPTCYP3A4 | |
| SCHEMBL7933665 | 0.78 | DGAT1 (0.48) | KDM4EALDH1A1HPGDMAPTCYP3A4 | |
| SCHEMBL7931184 | 0.77 | KMT2A (0.42) | KDM4EALDH1A1HPGDMAPTCYP3A4 | |
| SCHEMBL7931186 | 0.77 | KMT2A (0.42) | KDM4EALDH1A1HPGDMAPTCYP3A4 | |
| SCHEMBL7109287 | 0.75 | GAA (0.41) | TSHRKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL7020494 | 0.75 | MAPT (0.41) | TSHRKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL7017572 | 0.75 | MAPT (0.41) | TSHRKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL8304677 | 0.71 | NPSR1 (0.50) | KMT2ALMNANPSR1 | |
| SCHEMBL7762961 | 0.70 | NPSR1 (0.39) | TSHRKDM4EALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698494-A | Substituted N-phenylglutarimides and N-phenylglutaramides, their preparation and use | BASF AKTIENGESELLSCHAFT (DE) | 1997-12-16 | — | — | US | disclosed |