Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8529545 | 1.00 | L3MBTL1 (0.48) | L3MBTL1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL10907318 | 0.88 | L3MBTL1 (0.50) | L3MBTL1MEN1KMT2AALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL8724952 | 0.86 | ALDH1A1 (0.58) | L3MBTL1MEN1KMT2AALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL8724956 | 0.86 | ALDH1A1 (0.58) | L3MBTL1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL1572954 | 0.86 | L3MBTL1 (0.56) | L3MBTL1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL30619954 | 0.86 | L3MBTL1 (0.56) | L3MBTL1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL27583161 | 0.84 | MAPT (0.47) | L3MBTL1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| Acetamide SCHEMBL4985827 | 0.84 | L3MBTL1 (0.52) | L3MBTL1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL28448773 | 0.83 | MAPK1 (0.46) | L3MBTL1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL960746 | 0.82 | L3MBTL1 (0.53) | L3MBTL1MEN1KMT2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705257-B1 | AMINOACID DERIVATIVES AS NO SYNTHASE INHIBITORS | WELLCOME FOUND (GB) | 1998-03-11 | — | — | EP | disclosed |
| EP-0705257-A1 | AMINOACID DERIVATIVES AS NO SYNTHASE INHIBITORS | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000505-A1 | AMINOACID DERIVATIVES AS NO SYNTHASE INHIBITORS | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-01-05 | — | — | WO | disclosed |