Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1357107 | 0.97 | — | — | |
| SCHEMBL28338459 | 0.87 | LMNA (0.37) | THRBLMNA | |
| SCHEMBL27516876 | 0.87 | LMNA (0.37) | THRBLMNA | |
| SCHEMBL29109043 | 0.84 | — | — | |
| SCHEMBL4202345 | 0.84 | THRB (0.67) | THRBLMNADPP4ALDH1A1 | |
| SCHEMBL28789451 | 0.82 | LMNA (0.50) | THRBLMNADPP4ALDH1A1 | |
| SCHEMBL77663 | 0.80 | — | — | |
| SCHEMBL28656406 | 0.76 | THRB (0.43) | THRB | |
| SCHEMBL240703 | 0.75 | — | — | |
| SCHEMBL28957646 | 0.75 | THRB (0.56) | THRBLMNADPP4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874316-A | MEMBRANE COMPRISING TWO LAYERS, CLOSELY PACKED ARRAY OF AMPHIPHILIC MOLECULES AND PLURALITY OF GRAMICIDIN IONOPHORES COMPRISING MEMBRANE SPANNING SYSTEM, ATTACHED RECEPTOR MOLECULES; BINDING OF ANALYTE TO RECEPTOR CHANGES ION FLOW | AUSTRALIAN MEMBRANE BIOTECHNOLOGY RESEARCH INSTITUTE (AU) | 1999-02-23 | — | — | US | disclosed |
| US-5840083-A | A MEDICAL EQUIPMENT FOR GRAFTING IN MAMMALIAN BODY COMPRISING AN AMPHIPHILIC COATINGS HAVING AN ANTIBODIES RECEPTOR MOLECULE CONJUGATED TO A SUPPORTS LIPIDS AND MEMBRANE PROTEIN; ION CONDUCTIVITY | F.B. RICE & CO. (AU) | 1998-11-24 | — | — | US | disclosed |
| EP-0455705-B1 | RECEPTOR MEMBRANES AND IONOPHORE GATING | AU MEMBRANE & BIOTECH RES INST (AU) | 1997-05-28 | — | — | EP | disclosed |
| EP-0770874-A2 | Receptor membranes and ionophore gating | AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY RESEARCH INSTITUTE (AU) | 1997-05-02 | — | — | EP | disclosed |
| US-5443955-A | Provides device for implantation in mammalian body | AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY RESEARCH INSTITUTE (AU) | 1995-08-22 | — | — | US | disclosed |
| EP-0455705-A4 | RECEPTOR MEMBRANES AND IONOPHORE GATING | AU MEMBRANE & BIOTECH RES INST (AU) | 1992-09-16 | — | — | EP | disclosed |
| EP-0455705-A1 | RECEPTOR MEMBRANES AND IONOPHORE GATING. | AU MEMBRANE & BIOTECH RES INST (AU) | 1991-11-13 | — | — | EP | disclosed |
| WO-1990008783-A1 | RECEPTOR MEMBRANES AND IONOPHORE GATING | AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY RESEARCH INSTITUTE (AU) | 1990-08-09 | — | — | WO | disclosed |