Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 12/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8533030 | 0.84 | SLC9A1 (0.42) | SLC9A1CYP3A4 | |
| SCHEMBL8533178 | 0.83 | SLC9A1 (0.45) | SLC9A1 | |
| SCHEMBL8585538 | 0.82 | ALDH1A1 (0.36) | — | |
| SCHEMBL8533216 | 0.81 | SLC9A1 (0.47) | SLC9A1CYP3A4 | |
| SCHEMBL8528602 | 0.80 | SLC9A1 (0.41) | SLC9A1 | |
| SCHEMBL8529433 | 0.80 | SLC9A1 (0.48) | SLC9A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8580832 | 0.79 | SLC9A1 (0.45) | SLC9A1CYP3A4 | |
| SCHEMBL8528555 | 0.78 | SLC9A1 (0.48) | SLC9A1 | |
| SCHEMBL8530489 | 0.78 | SLC9A1 (0.46) | SLC9A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8529686 | 0.77 | SLC9A1 (0.52) | SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840761-A | Alkylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-11-24 | — | — | US | disclosed |
| EP-0699663-B1 | Alkyl-benzoylguanidine derivatives | MERCK PATENT GMBH (DE) | 1998-11-04 | — | — | EP | disclosed |
| EP-0699663-A1 | Alkyl-benzoylguanidine derivatives | MERCK PATENT GmbH (DE) | 1996-03-06 | — | — | EP | disclosed |