SCHEMBL85297

SCHEMBL85297

CNc1ccc[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27587457 0.97
Pyridine SCHEMBL28290162 0.85 TSHR (0.36)
SCHEMBL3194321 0.77 DAO (0.35)
SCHEMBL1566543 0.74
SCHEMBL14869511 0.74 LMNA (0.47)
SCHEMBL9402161 0.72
SCHEMBL5136344 0.72
SCHEMBL1482895 0.72
SCHEMBL9918670 0.72
SCHEMBL8003798 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110669058-A Tricyclic quinolone carboxylic acid and preparation method thereof 江西农业大学 2020-01-10 CN claimed
CN-105884777-B One kind acts on EGFR sensitizing mutation kinases EGFRL858R, EGFR(d746‑750)6 substituted amino purine class compounds and its application 温州医科大学 2017-11-10 CN claimed
EP-0106243-B1 AZOLYL-METHYL AMINES, THEIR PREPARATION AND THEIR USE IN MICROBICIDE COMPOSITIONS BAYER AG (DE) 1986-05-28 EP claimed
EP-0106243-A1 Azolyl-methyl amines, their preparation and their use in microbicide compositions BAYER AG (DE) 1984-04-25 EP claimed
JP-5034886-A None JP disclosed
US-12479813-B2 Method of therapeutically treating cancer ADT PHARMACEUTICALS, LLC (US) 2025-11-25 US disclosed
CN-111562729-B Light-responsive low-molecular material, adhesive, toner, and image forming method 柯尼卡美能达株式会社 2024-04-05 CN disclosed
CN-114805389-B Tricyclic dihydro-imidazo pyrimidinone derivatives, preparation method, pharmaceutical compositions and uses thereof 上海赛默罗生物科技有限公司 2023-08-29 CN disclosed
US-11702398-B2 Photoresponsive low-molecular weight material, adhesive, toner, and image forming method Konica Minolta, Inc. (JP) 2023-07-18 US disclosed
EP-3233794-B1 INDENYL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND MEDICAL USES THEREOF ADT PHARMACEUTICALS LLC (US) 2023-02-01 EP disclosed
CN-114213395-B Pyrimidone acyl piperazine compound and preparation method and application thereof 山东大学 2022-10-25 CN disclosed
US-20220315553-A1 INDENYL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF ADT PHARMACEUTICALS, LLC (US) 2022-10-06 US disclosed
US-4752610-A N-(pyrrol-1-yl)pyridinamines having memory enhancing properties HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1988-06-21 US disclosed
EP-0226099-A2 N-(pyrrol-1-yl)pyridinamines, a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1987-06-24 EP disclosed
US-4599427-A FUNGICIDES BACTERICIDES SLIMICIDES ALGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1986-07-08 US disclosed
EP-0106243-B1 AZOLYL-METHYL AMINES, THEIR PREPARATION AND THEIR USE IN MICROBICIDE COMPOSITIONS BAYER AG (DE) 1986-05-28 EP disclosed
EP-0106243-B1 AZOLYL-METHYL AMINES, THEIR PREPARATION AND THEIR USE IN MICROBICIDE COMPOSITIONS BAYER AG (DE) 1986-05-28 EP disclosed
EP-0106243-A1 Azolyl-methyl amines, their preparation and their use in microbicide compositions BAYER AG (DE) 1984-04-25 EP disclosed
EP-0106243-A1 Azolyl-methyl amines, their preparation and their use in microbicide compositions BAYER AG (DE) 1984-04-25 EP disclosed
EP-0106243-A1 Azolyl-methyl amines, their preparation and their use in microbicide compositions BAYER AG (DE) 1984-04-25 EP disclosed