Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.30 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7922369 | 0.79 | CYP1A2 (0.41) | ADORA3 | |
| SCHEMBL29377586 | 0.79 | CYP1A2 (0.41) | ADORA3 | |
| SCHEMBL8269416 | 0.78 | ALDH1A1 (0.44) | ADORA3 | |
| SCHEMBL14640219 | 0.76 | CYP2A6 (0.41) | MAPKAPK2RPS6KA3CSNK2A1PLK3 | |
| SCHEMBL13154918 | 0.73 | SCN10A (0.36) | — | |
| SCHEMBL15478309 | 0.73 | VCP (0.40) | — | |
| SCHEMBL16729146 | 0.73 | AXL (0.44) | — | |
| SCHEMBL16720736 | 0.72 | KDM4E (0.32) | MAPKAPK2RPS6KA3CSNK2A1PLK3 | |
| SCHEMBL13188450 | 0.71 | FABP6 (0.32) | ADORA3 | |
| SCHEMBL24690029 | 0.71 | DAO (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012083164-A1 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2012-06-21 | — | — | WO | disclosed |
| EP-2455376-A1 | Heterocyclic compounds as inhibitors of hepatitis C virus (HCV) | Abbott Laboratories (US) | 2012-05-23 | — | — | EP | disclosed |
| EP-2368890-A1 | Hepatitis C virus inhibitors | Abbott Laboratories (US) | 2011-09-28 | — | — | EP | disclosed |