Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 2/20 | 0.46 |
| ▸ | GNPAT | O15228 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8530388 | 1.00 | ALB (0.46) | ALBGNPATKDM4EMAPTTHRB | |
| SCHEMBL8530392 | 1.00 | ALB (0.46) | ALBGNPATKDM4EMAPTTHRB | |
| SCHEMBL6801056 | 0.91 | ALB (0.53) | ALBGNPATKDM4EMAPTTHRB | |
| SCHEMBL6931278 | 0.85 | GNPAT (0.57) | ALBGNPATSMN1; SMN2TSHRMME | |
| SCHEMBL468905 | 0.85 | GNPAT (0.57) | ALBGNPATSMN1; SMN2TSHRMME | |
| SCHEMBL468907 | 0.85 | GNPAT (0.57) | ALBGNPATSMN1; SMN2TSHRMME | |
| SCHEMBL17783704 | 0.85 | ROCK2 (0.44) | SMN1; SMN2TSHRACACBALDH1A1 | |
| SCHEMBL9345640 | 0.84 | LMNA (0.56) | GNPATKDM4EMAPTTHRBALOX15 | |
| SCHEMBL4062224 | 0.84 | LMNA (0.56) | GNPATKDM4EMAPTTHRBALOX15 | |
| SCHEMBL9350155 | 0.84 | LMNA (0.56) | GNPATKDM4EMAPTTHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807875-A | OBESITY THERAPY | DR. KARL THOMAE GMBH (DE) | 1998-09-15 | — | — | US | disclosed |
| US-5616620-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-04-01 | — | — | US | disclosed |