Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4947264 | 0.93 | ALDH1A1 (0.55) | ALDH1A1HPGDHSD17B10CNR2CA12 | |
| SCHEMBL5725083 | 0.92 | ALDH1A1 (0.54) | ALDH1A1HPGDHSD17B10CNR2CA12 | |
| SCHEMBL5725098 | 0.92 | ALDH1A1 (0.54) | ALDH1A1HPGDHSD17B10CNR2CA12 | |
| SCHEMBL5724723 | 0.89 | ALDH1A1 (0.56) | ALDH1A1HPGDHSD17B10CNR2CA12 | |
| SCHEMBL5726660 | 0.87 | ALDH1A1 (0.63) | ALDH1A1HPGDHSD17B10CNR2CA12 | |
| SCHEMBL5725270 | 0.86 | CA12 (0.48) | TLR7CA12CA1CA2CA4 | |
| SCHEMBL5726215 | 0.85 | CA12 (0.50) | ALDH1A1HPGDHSD17B10CNR2CA12 | |
| SCHEMBL5725967 | 0.84 | ALDH1A1 (0.49) | ALDH1A1HPGDHSD17B10CNR2CA12 | |
| SCHEMBL5727158 | 0.84 | TAS2R14 (0.46) | TLR7CA12CA1CA2CA4 | |
| SCHEMBL5725536 | 0.84 | ALDH1A1 (0.52) | ALDH1A1HPGDHSD17B10CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946501-A1 | PREVENTION OF LOSS AND RESTORATION OF BONE MASS BY CERTAIN PROSTAGLANDIN AGONISTS | PFIZER INC. (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998028264-A1 | PREVENTION OF LOSS AND RESTORATION OF BONE MASS BY CERTAIN PROSTAGLANDIN AGONISTS | PFIZER INC. (US) | 1998-07-02 | — | — | WO | disclosed |